Synthesis and Characterization of Some New Formazan Derivatives From 2-Amino-4-Hydroxy-6-Methyl Pyrimidine and Study the Biological Activity (Anti-Bacteria and Anti-Cancer)

Main Article Content

Abdullah Shakir Ogbemudia
Shaimaa Adnan

Abstract

This study involves a synthesis of some formazan derivatives starting from react chloro acetyl chlorid with 2-amino-4-hydroxy-6-methyl pyrimidine to gate compound (a), (a) react with hydrazine hydrate to give compound (b) also (b) react with 3-4-dimethoxy benzaldehyd to product Schiff base derivative (c) then (c) react with deferent amin derivatives to get formazan derivatives. All these compounds characterized by 13C-NMR, FTIR, 1HMNR. After that, we study the biological activity for all formazan derivatives toward two different kinds of bacteria and anti-cancer.

Article Details

How to Cite
1.
Ogbemudia A, Adnan S. Synthesis and Characterization of Some New Formazan Derivatives From 2-Amino-4-Hydroxy-6-Methyl Pyrimidine and Study the Biological Activity (Anti-Bacteria and Anti-Cancer). IJPQA [Internet]. 25Jan.2013 [cited 2Jul.2020];11(01):40-5. Available from: https://www.ijpqa.com/index.php/IJPQA/article/view/962
Section
Research Article