Synthesis and Characterization of Some 4- Substituted Thiazolidinone Derivatives

Zainab Ryad Magtoof, Mahmood Shakir Magtoof

Abstract


This study is concerned with the synthesis and characterization of 4-thiazolidinone derivatives (3a-3e). These compounds were prepared by reacting mercaptoacetic acid with the appropriate Schiff bases (imines) by heating at 50-60 °C in chloroform with moderate yields (51- 75 %). The structures of these 4-thiazolidinone derivatives were established on the basis of spectral studies using IR, 1H-NMR, 13C-NMR, and13C-NMR DEPT.

Keywords


Imines, NMR spectroscopy, Synthesis, Thiazolidinones.

Full Text:

PDF


DOI: http://dx.doi.org/10.25258/ijpqa.10.4.12

Refbacks

  • There are currently no refbacks.


Copyright (c) 2019 International Journal of Pharmaceutical Quality Assurance

License URL: https://creativecommons.org/licenses/by-nc-nd/4.0