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Aim: This study aimed to evaluate changes in serum levels of some elements (phosphorus and chloride ions) and relationship with hypothyroidism, hyperthyroidism; and euthyroidism as a control groups. Method: Analysis of serum phosphorus and chloride were done by enzymatic methods using AGAPPE kit. Result: Patients with hyperthyroidism and hypothyroidism showed highly significant increase in serum phosphorus levels (p andGLT; 0.001). In case of hypo- and hyperthyroidism significant difference could not be obtained among euthyroidism and patients (p>0.05) in chloride level. While a positive correlation with thyroid stimulating hormone (TSH), serum phosphorous and chloride in case of hypothyroidism. In hyperthyroid patients, the correlation was negative for phosphorous and positive for chloride, also none of correlations were statistically significant (p>0.05). Conclusion: Thyroid patients should be regularly checked for serum electrolytes. Early discovery and management can prevent the further complications and will be useful during the controlling of thyroid patients.
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