Development and Validation of UV Spectrophotometric Method For The Estimation of Finasteride Drug

Divya Sanganabhatla, R Shyam Sunder

Abstract


A simple, accurate, precise, reproducible, highly sensitive, an economic spectrophotometric method has been developed for the estimation of finasteride. UV spectrophotometric method is based on the measurement of absorption at a maximum wavelength of 255 nm. The developed method was validated with respect to linearity, accuracy (recovery), Precision (inter and intraday variations), LOD and LOQ. Beer’s law was obeyed in the concentration range of 5 – 25 μg/mL with a correlation coefficient of 0.9933. Results of the analysis were validated statistically and by recovery study. Hence the developed and validated method can be used for estimation of finasteride.

Keywords


Development, Finasteride, UV Spectroscopy, Validation.

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DOI: http://dx.doi.org/10.25258/ijpqa.10.4.6

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