Immunological study of Parvovirus B19 in aborted women in Al-Ramadi city

Muntaha M.H. Al-Alouci, Huda Rafaa Al-Alwani

Abstract


Background: Infection of parvovirus is highly spread that may affect 1-5% of pregnant women mainly in normal pregnancy outcomes. Infection is almost sub-immunogenic level and the viral copies are usually under control of immune system especially the antibodies against B19 V. IgM of parvovirus appears with 2-3 days of infection and remain until 6 months, while IgG appears after few days of IgM detection and remain present for life. The aim of the study: To determine the prevalence of parvovirus B19 infection and if the women are immunized or not against this virus infection through testing process for both IgM and IgG. Patients and methods: Fifty pregnant women with spontaneous abortion were conducted in the study. Venous blood samples were collected from all participants after the abortion and parvovirus IgM and IgG titer were measured by ELISA method. Results: All participants of aborted women were negative IgM antibody, while IgG antibody was positive in 58% from total number and remaining percent was negative for IgG. Conclusions: Infection with parvovirus give the women immune response and become immunized against Parvovirus this mean the infection present in our community. Therefore, serological screenings must be involved to routine work to detect the infections in childbearing age group of women.

Keywords


Parvovirus B19, IgM, IgG, aborted women, ELISA.

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DOI: http://dx.doi.org/10.25258/ijpqa.10.2.8

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